Experienced Exporter of Beta-Methyl Vinyl Phosphate CAS 90776-59-3 Used in Fine Chemicals

Basic Info

Model NO.	CAS 90776-59-3
CAS No.	90776-59-3
Formula	C29h27n2o10p
EINECS	618-646-2
Type	Pharmaceutical Intermediates
Appearance	Powder
Quality	Refined
Colour	White
Molecular Weight	594.51
Melting Point	126-130ºC
Content	Greater Than or Equal to 99%
Transport Package	Barrel or Bag
Specification	20Kg/Barrel or as required
Trademark	Juyuan
Origin	Xinxiang, Henan
Production Capacity	200 Tons/Month

Product Description

Brief Introduction

Brief Introduction
Name	Beta-Methyl Vinyl Phosphate
Synonyms	beta-Methyl vinyl phosphate MAP
	(4R,5S,6S)-3-(Diphenyloxy)phosphoryloxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate
	(1R,5S,6S)-2-(diphenyloxy)phosphoryloxy-6-[(1R)-1-hydroxyethyl]-1-methyl-1-carbapen-2-em-3-carboxylate
	(1R,5R,6S)-6-[(1R)-1-Hydroxyethyl]-2-[(diphenylphosphono)-oxy]-1-methylcarbapen-2-em-3-carboxylic acid 4-nitrobenzyl ester
	[4R-[4α, 5β,6β(R*)]]-3-[(diphenoxyphosphinyl)oxy]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
	4-nitrobenzyl (4R,5R,6S)-3-[(diphenoxyphosphoryl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
CAS	90776-59-3
EINECS	618-646-2
Molecular Formula	C29H27N2O10P
Molecular Weight	594.51

Properties

Properties
Density	1.47±0.1 g/cm3(Predicted)
Melting Point	126-130ºC
Boling Point	722.4±60.0 °C(Predicted)
Flash Point	390.671°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	White Powder
Color	White to Off-White
pKa	14.36±0.20(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.653
Usage	Used as a pharmaceutical intermediate, also can be used for the preparation of pivol ester of tibipenem.
Packing	20kg/barrel(Lined with a plastic bag, sealed with an aluminum foil bag, and with a paper cylinder outside)
Specific spin	[α]D20 =+45°~+55°
PSA	167.23
LogP	2.13
Density	1.5±0.1 g/cm3
MDL Number	MFCD01318092
InChI	InChI=1/C29H27N2O10P/c1-18-25-24(19(2)32)28(33)30(25)26(29(34)38-17-20-13-15-21(16-14-20)31(35)36)27(18)41-42(37,39-22-9-5-3-6-10-22)40-23-11-7-4-8-12-23/h3-16,18-19,24-25,32H,17H2,1-2H3/t18-,19-,24-,25-/m1/s1

Product Description

Product Description

Beta-Methyl Vinyl Phosphate is a pharmaceutical intermediate that can be used to prepare tibipenem pivoxil. Tibipenem pivoxil, chemically known as (+) - (4R, 5S, 6S) - 6 - [(1R) - hydroxyethyl] - 4-methyl-7-oxo-3 [[1 - (2-thiazolin-2-yl) - 3-azacyclobutanyl] sulfur] - 1-azabicyclic [3.2.0] hept-2-en-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy) methyl ester, is a carbapenem antibiotic. After absorption in the intestinal tract, Tibipenem pivoxil is metabolized to Tibipenem, showing antibacterial activity.
Tibipenem has broad-spectrum antibacterial activity against gram-positive bacteria and gram-negative bacteria, including Staphylococcus, Streptococcus, Pneumococcus (including PRSP), and Moraxella catarrhalis (including β- Lactam producing bacteria), Haemophilus influenzae (including ampicillin resistant Haemophilus influenzae) have strong antibacterial activity. In particular, compared to previous oral antibiotics, tibpenem exhibits extremely strong antibacterial activity against pathogenic bacteria such as otitis media, paranasal sinusitis, and pneumonia in children, penicillin resistant pneumococci, and macrolide resistant pneumococci.
The mechanism of action of tibpenem is to inhibit the synthesis of bacterial cell walls, have high affinity for various bacterial penicillin binding proteins (PBPs), and play a bactericidal role.
Tibipenem has a higher affinity for PBP1A, 2X, or 2B of penicillin-resistant pneumococci than other oral antibiotics β- Lactam antibiotics.

Packaging & Transport

Packaging & Transport

Experienced Exporter of Beta-Methyl Vinyl Phosphate CAS 90776-59-3 Used in Fine Chemicals

Payment

Company Profile

Company profile

Xinxiang Juyuan Biological Technology is specialized in the manufacture, research and development of pharmaceutical intermediates and fine chemicals, such as Biapenem, and series intermediates of Penem.

The company is located in the economic development zone in Xinxiang City, Henan Province, enjoying a superior location and convenient transportation.The company is armed with top-notch technicians, advanced production equipments and testing instruments as well as perfect Q.C. system. Products are sold not only around China, but also to Europe and the US as well as the Asia-Pacific Region.Upholding the Strategic Policy of "Survive through Quality, Develop through Technology", we sincerely welcome the cooperation of friends from all walks of life for a bright future.

Experienced Exporter of Beta-Methyl Vinyl Phosphate CAS 90776-59-3 Used in Fine Chemicals

FAQ

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.

Q2:What's your MOQ?
A: Our MOQ starts from 1kg.

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A: Generally, it will take 3 to 5 days after receiving your advance payment.

Q5. Are you manufacturer or trade company?We are a comprehensive technology enterprise that focuses on the production and research and development of intermediates and fine chemicals.

Q6:How to contact us?You can choose your interested products and send inquiry to us.You can dial our telephone directly, you will get our reply.